Fresh air strikes pounded the rebel-held Syrian town of Douma on Saturday, completing 24 hours of carnage that killed at least 48 civilians, rescuers and a monitor said.
The bombing came after a 10-day truce between President Bashar Al Assad's regime and the rebels collapsed.
The offensive to reclaim Douma, the last pocket of resistance in the suburbs surrounding Damascus, also followed talks between Turkey, Russia and Iran, on Syria.
The three countries are active players in the conflict, yet on Wednesday they called for a lasting ceasefire.
It was not clear if Russia, the regime's main backer, or the Syrian Air Force had conducted the latest air strikes.
"The bombing has not stopped. We can't even count all the wounded," said Mohammed, a young doctor inside Douma.
"There are some wounded who we could not operate on in time, and they died," he added.
On Friday, the Syrian army launched a ground offensive on Douma's outskirts after talks sputtered over a rebel withdrawal.
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Regime forces have captured nearly all of Ghouta with a combination of ferocious bombing raids, which started on February 18, and negotiated withdrawals.
All that remains is Douma, the largest town, held by the Jaish Al Islam faction, home to tens of thousands.
The Britain-based Syrian Observatory for Human Rights said warplanes were hitting Douma on Saturday, as regime artillery fire hit neighbouring fields.
The Observatory said 40 people were killed on Friday, with eight more dying in the latest violence.
"The regime is trying to tighten the noose around Douma from the west, east, and south," said Observatory chief Rami Abdel Rahman.
Moscow announced a deal with Jaish Al Islam last Sunday, ushering in three consecutive days of evacuations from Douma that saw nearly 3,000 fighters and civilians taken in buses to Idlib, northern Syria.
But the exit plan stalled after reports that Jaish Al Islam remained divided over a withdrawal, and heavy bombing started to hit Douma on Friday afternoon.
The Observatory said there were dozens of air strikes, including some suspected to have been carried out by Russian warplanes.
Regime forces were locked in violent clashes with Jaish Al Islam rebels in agricultural areas to the southwest and east of the town, the monitor said.
A medic inside Douma described chaos at the local hospital as wounded and dead were brought in.
"The hospital is in a state of panic," the medic said. "Dentists are carrying out emergency surgeries. Dead bodies are being brought in pieces and are unrecognisable."
A doctor inside the town said state television was broadcasting the bombardment live.
"It feels like we're back in the days of the Gaza war" when Israel was bombing the Palestinian enclave and people around the world watched, he said, giving his name only as Mohammed.
State news agency SANA said Syrian air strikes hit the town on Friday in response to deadly rebel mortar fire from Douma.
It said mortar shells hit several suburbs of the capital and killed at least four people and wounded more than a dozen.
But Jaish Al Islam spokesman Hamza Bayraqdar in a statement late Friday denied that the group had targeted any Damascus neighbourhoods.
The air and ground offensive on Eastern Ghouta has killed more than 1,600 civilians and caused an international outcry.
The enclave on the eastern edge of Damascus had escaped government control since 2012 and, although it had shrunk over the years, it still covered sizeable territory two months ago.
The daily air raids kept residents cowering in basements for weeks and a ground assault soon sliced the area into three isolated pockets, each held by different rebel factions.
The first two were evacuated under Russian-brokered deals last month that saw more than 46,000 rebels and civilians moved to the northwestern province of Idlib, which the regime does not control.
Tens of thousands of people also fled through humanitarian corridors opened by Russia and Syrian troops.
Some have already returned to their devastated neighbourhoods, while others are staying in crowded shelters.
As talks over the third and final pocket of Douma dragged on, Russia and Syria's regime threatened Jaish Al Islam with a renewed military assault if they did not agree to withdraw.
Those still trapped in Douma had been nervous that any attempt to renege on plans to leave would prompt Russia and regime warplanes to resume deadly strikes.
In Ankara on Wednesday, the Turkish, Russian and Iranian presidents said there was "no alternative to the Syrian National Dialogue Congress", the Moscow-sponsored peace effort widely seen as a rival to the UN's Geneva process.
In a joint statement, Recep Tayyip Erdogan, Vladimir Putin and Hassan Rouahni said the so-called Astana initiative "had been the only effective international initiative that had helped reduce violence across Syria and had contributed to peace and stability in Syria".
The talks came just hours after US President Donald Trump signalled an exit soon from Syria, saying he wanted to "bring our troops back home".
A State of Passion
Directors: Carol Mansour and Muna Khalidi
Stars: Dr Ghassan Abu-Sittah
Rating: 4/5
Fines for littering
In Dubai:
Dh200 for littering or spitting in the Dubai Metro
Dh500 for throwing cigarette butts or chewing gum on the floor, or littering from a vehicle.
Dh1,000 for littering on a beach, spitting in public places, throwing a cigarette butt from a vehicle
In Sharjah and other emirates
Dh500 for littering - including cigarette butts and chewing gum - in public places and beaches in Sharjah
Dh2,000 for littering in Sharjah deserts
Dh500 for littering from a vehicle in Ras Al Khaimah
Dh1,000 for littering from a car in Abu Dhabi
Dh1,000 to Dh100,000 for dumping waste in residential or public areas in Al Ain
Dh10,000 for littering at Ajman's beaches
Analysis
Members of Syria's Alawite minority community face threat in their heartland after one of the deadliest days in country’s recent history. Read more
The specs
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THE BIO:
Sabri Razouk, 74
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Married, father of six
Favourite exercise: Bench press
Must-eat weekly meal: Steak with beans, carrots, broccoli, crust and corn
Power drink: A glass of yoghurt
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The specs: 2019 Haval H6
Price, base: Dh69,900
Engine: 2.0-litre turbocharged four-cylinder
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Power: 197hp @ 5,500rpm
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Fuel economy, combined: 7.0L / 100km
The specs
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Haemoglobin disorders explained
Thalassaemia is part of a family of genetic conditions affecting the blood known as haemoglobin disorders.
Haemoglobin is a substance in the red blood cells that carries oxygen and a lack of it triggers anemia, leaving patients very weak, short of breath and pale.
The most severe type of the condition is typically inherited when both parents are carriers. Those patients often require regular blood transfusions - about 450 of the UAE's 2,000 thalassaemia patients - though frequent transfusions can lead to too much iron in the body and heart and liver problems.
The condition mainly affects people of Mediterranean, South Asian, South-East Asian and Middle Eastern origin. Saudi Arabia recorded 45,892 cases of carriers between 2004 and 2014.
A World Health Organisation study estimated that globally there are at least 950,000 'new carrier couples' every year and annually there are 1.33 million at-risk pregnancies.
EMERGENCY PHONE NUMBERS
Estijaba – 8001717 – number to call to request coronavirus testing
Ministry of Health and Prevention – 80011111
Dubai Health Authority – 800342 – The number to book a free video or voice consultation with a doctor or connect to a local health centre
Emirates airline – 600555555
Etihad Airways – 600555666
Ambulance – 998
Knowledge and Human Development Authority – 8005432 ext. 4 for Covid-19 queries
The specs
Engine: Four electric motors, one at each wheel
Power: 579hp
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Transmission: Single-speed automatic
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Our legal consultant
Name: Hassan Mohsen Elhais
Position: legal consultant with Al Rowaad Advocates and Legal Consultants.
Need to know
When: October 17 until November 10
Cost: Entry is free but some events require prior registration
Where: Various locations including National Theatre (Abu Dhabi), Abu Dhabi Cultural Center, Zayed University Promenade, Beach Rotana (Abu Dhabi), Vox Cinemas at Yas Mall, Sharjah Youth Center
What: The Korea Festival will feature art exhibitions, a B-boy dance show, a mini K-pop concert, traditional dance and music performances, food tastings, a beauty seminar, and more.
For more information: www.koreafestivaluae.com
The specs
Engine: 2.0-litre 4-cyl, 48V hybrid
Transmission: eight-speed automatic
Power: 325bhp
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Price: Dh359,000
On sale: now
Company profile: buybackbazaar.com
Name: buybackbazaar.com
Started: January 2018
Founder(s): Pishu Ganglani and Ricky Husaini
Based: Dubai
Sector: FinTech, micro finance
Initial investment: $1 million
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Killing of Qassem Suleimani