Tottenham v Manchester City (7.30pm): The match of the weekend sees Spurs, led by new manager Nuno Espirito Santo, take on the champions. While £100m signing Jack Grealish will make his league debut for the visitors, the big question mark of the weekend is whether Harry Kane - also linked with a move to City - is involved for Spurs. Prediction: Spurs 1 City 3.
SATURDAY - Manchester United v Leeds (3.30pm): A huge season for United manager Ole Gunnar Solskjaer, who has been backed big in the transfer market with the arrival of Jadon Sancho and Raphael Varane. Macelo Bielsa's side, though, showed last season they are capable of bringing down the big beasts. Prediction: Man United 2 Leeds 1.
Burnley v Brighton (6pm): The two clubs who occupied the spots just outside relegation last season meet at the start of what is likely to be another struggle to survive. While Brighton have broken their transfer record to bring in midfielder Enock Mwepu from Salzburg for a fee in excess of £20m, Burnley are in dire need of some fresh talent. Prediction: Burnley 0 Brighton 1.
Chelsea v Crystal Palace (6pm): The European champions kick off their new campaign boosted by the impending big-money return of striker Romelu Lukaku. A new era begins for Palace, with Patrick Vieira now in the managerial hotseat having taken over from Roy Hodgson but still reliant on Wilfried Zaha for their attacking flair. Prediction: Chelsea 3 Palace 0.
Everton v Southampton (6pm): Rafa Benitez has never been one to shirk a challenge but the former Liverpool manager faces a huge battle to win over hearts and minds at new club Everton. It is vital he gets off to a winning start here in front of a sceptical Goodison Park faithful. Everton 2 Southampton 1.
Leicester v Wolves (6pm): Mixed emotions for Leicester going into the new season. They do have one trophy already in the bag after beating Manchester City in the Community Shield, but the serious injury to defender Wesley Fofana was a blow. Wolves will be hoping striker Raul Jimenez has finally recovered from his fractured skull. Prediction: Leicester 3 Wolves 2.
Watford v Aston Villa (6pm): All eyes on Villa to see how they react to the loss of Jack Grealish. Striker Danny Ings, plus wingers Emiliano Buenia and Leon Bailey have all arrived on big-money deals to replace their attacking talisman. Top-flight returnees Watford will be aiming to give the Villa new boys a debut to forget. Prediction: Watford 2 Villa 2.
Norwich v Liverpool (8.30pm): A quiet summer in the transfer market and an injury to full-back Andy Robertson means Liverpool fans might be forgiven for harbouring a few worries going into the new season. Manager Jurgen Klopp insists he is happy with the strength of his squad, although the early alarm bells will be ringing if they fall short here at Carrow Road. Prediction: Norwich 0 Liverpool 2.
SUNDAY - Newcastle v West Ham (2pm): The arrival of last season's loan star Joe Willock on a permanent deal is a huge boost for Magpies manager Steve Bruce while handing Callum Wilson the famous No 9 shirt was a savvy move. Last season's surprise packages West Ham are first up at St James' Park. Prediction: Newcastle 2 West Ham 1.
Tottenham v Manchester City (7.30pm): The match of the weekend sees Spurs, led by new manager Nuno Espirito Santo, take on the champions. While £100m signing Jack Grealish will make his league debut for the visitors, the big question mark of the weekend is whether Harry Kane - also linked with a move to City - is involved for Spurs. Prediction: Spurs 1 City 3.
SATURDAY - Manchester United v Leeds (3.30pm): A huge season for United manager Ole Gunnar Solskjaer, who has been backed big in the transfer market with the arrival of Jadon Sancho and Raphael Varane. Macelo Bielsa's side, though, showed last season they are capable of bringing down the big beasts. Prediction: Man United 2 Leeds 1.
Burnley v Brighton (6pm): The two clubs who occupied the spots just outside relegation last season meet at the start of what is likely to be another struggle to survive. While Brighton have broken their transfer record to bring in midfielder Enock Mwepu from Salzburg for a fee in excess of £20m, Burnley are in dire need of some fresh talent. Prediction: Burnley 0 Brighton 1.
Chelsea v Crystal Palace (6pm): The European champions kick off their new campaign boosted by the impending big-money return of striker Romelu Lukaku. A new era begins for Palace, with Patrick Vieira now in the managerial hotseat having taken over from Roy Hodgson but still reliant on Wilfried Zaha for their attacking flair. Prediction: Chelsea 3 Palace 0.
Everton v Southampton (6pm): Rafa Benitez has never been one to shirk a challenge but the former Liverpool manager faces a huge battle to win over hearts and minds at new club Everton. It is vital he gets off to a winning start here in front of a sceptical Goodison Park faithful. Everton 2 Southampton 1.
Leicester v Wolves (6pm): Mixed emotions for Leicester going into the new season. They do have one trophy already in the bag after beating Manchester City in the Community Shield, but the serious injury to defender Wesley Fofana was a blow. Wolves will be hoping striker Raul Jimenez has finally recovered from his fractured skull. Prediction: Leicester 3 Wolves 2.
Watford v Aston Villa (6pm): All eyes on Villa to see how they react to the loss of Jack Grealish. Striker Danny Ings, plus wingers Emiliano Buenia and Leon Bailey have all arrived on big-money deals to replace their attacking talisman. Top-flight returnees Watford will be aiming to give the Villa new boys a debut to forget. Prediction: Watford 2 Villa 2.
Norwich v Liverpool (8.30pm): A quiet summer in the transfer market and an injury to full-back Andy Robertson means Liverpool fans might be forgiven for harbouring a few worries going into the new season. Manager Jurgen Klopp insists he is happy with the strength of his squad, although the early alarm bells will be ringing if they fall short here at Carrow Road. Prediction: Norwich 0 Liverpool 2.
SUNDAY - Newcastle v West Ham (2pm): The arrival of last season's loan star Joe Willock on a permanent deal is a huge boost for Magpies manager Steve Bruce while handing Callum Wilson the famous No 9 shirt was a savvy move. Last season's surprise packages West Ham are first up at St James' Park. Prediction: Newcastle 2 West Ham 1.
Tottenham v Manchester City (7.30pm): The match of the weekend sees Spurs, led by new manager Nuno Espirito Santo, take on the champions. While £100m signing Jack Grealish will make his league debut for the visitors, the big question mark of the weekend is whether Harry Kane - also linked with a move to City - is involved for Spurs. Prediction: Spurs 1 City 3.