Tobias Harris drove in the final dagger as the Philadelphia 76ers thwarted a late Los Angeles Lakers rally to hand the reigning NBA champions their first road defeat of the season by 107-106. In a bruising heavyweight clash, the Eastern Conference leading Sixers made a statement against the league-leading Lakers. "Some people think we haven't played anybody," Harris said. "For us, we wanted to go against the champs. We wanted to see where we're at." Joel Embiid scored 28 points, Ben Simmons notched a triple-double of 17 points, 11 rebounds and 10 assists and Harris, fed by Seth Curry, sealed the victory with a pull-up jump shot with three seconds remaining. The Lakers, who had won a franchise-best 10 road games to start the season, nearly kept the streak alive despite trailing by 14 points in the fourth quarter. The Lakers, down by 12 with 3:07 remaining, produced a 13-0 scoring run launched by Alex Caruso's finger-roll layup. After three-pointers from Caruso, Dennis Schroder and Kentavious Caldwell-Pope, Anthony Davis gave the Lakers a 106-105 lead on a layup set up by LeBron James. After a timeout, Philadelphia inbounded the ball with 11.2 seconds remaining. They got the ball to Harris, who drove left and fired. Meanwhile, the Brooklyn Nets, with a big night from their big three, escaped with a 132-128 overtime victory over the Hawks in Atlanta. Kevin Durant scored 32 points, James Harden added a double-double of 31 points and 15 assists with eight rebounds and Kyrie Irving added 26 points for Brooklyn, who won their third straight.