Covifenz was manufactured by biopharma company Medicago and GlaxoSmithKline. Getty Images
Covifenz was manufactured by biopharma company Medicago and GlaxoSmithKline. Getty Images
Covifenz was manufactured by biopharma company Medicago and GlaxoSmithKline. Getty Images
Covifenz was manufactured by biopharma company Medicago and GlaxoSmithKline. Getty Images

Canada to use world’s first plant-based Covid vaccine


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Canadian regulators on Thursday announced that the country will use the world’s first plant-derived Covid-19 vaccine.

The vaccine, named Covifenz, was jointly developed by Medicago, a biopharma company owned by Mitsubishi Chemical and Philip Morris, based in Quebec City, and GlaxoSmithKline.

The two-dose vaccine can be given to adults between 18 and 64 years old.

The Quebec-based privately held company has an agreement to supply up to 76 million doses to the Canadian government.

“We're at a stage where we're ramping up capacity to meet the supply agreement,” said Marc-Andre D’Aoust, Medicago's executive vice president of innovation, development and medical affairs.

Medicago said it was committed to fulfilling the order as soon as possible.

The decision was based on a study of 24,000 adults that found the vaccine was 71 per cent effective at preventing Covid-19.

Side effects were mild and included fever and fatigue.

The study was conducted before the Omicron variant emerged.

Medicago uses plants as living factories to grow virus-like particles, which copy the spike protein that coats the coronavirus. The particles are removed from the plants’ leaves and then purified.

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  • Dr Habib advised patients with chronic health problems to buy a pulse oximeter to monitor their blood oxygen levels, an important signal that could help diagnose an infection from afar. EPA
    Dr Habib advised patients with chronic health problems to buy a pulse oximeter to monitor their blood oxygen levels, an important signal that could help diagnose an infection from afar. EPA
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    'These wearable devices won’t give you a specific diagnosis for an illness or disease, but it will show you if something is unusual,' said Dr Habib. Antonie Robertson/The National
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    Fitness trackers can record daily steps, sleep patterns, calorie intake, mood and progress towards exercise goals. AP
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    Tech firm Biospectal developed the OptiBP app that allows blood pressure to be monitored effectively using a smartphone’s camera. Photo: Biospectal
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An immune-boosting chemical called an adjuvant, made by British partner GlaxoSmithKline, is then added to the shots.

Medicago plans to test the shot in children and as a booster dose for adults, Mr D’Aoust said.

The immunisation was granted fast-track designation by the US Food and Drug Administration in February last year.

The Canadian government on Thursday announced it was lifting the emergency powers it enacted more than a week ago to bring street protests under control, with Prime Minister Justin Trudeau saying the authority is no longer needed.

The protests were initially against Canada’s Covid-19 vaccination requirements for lorry drivers transporting goods across the US border, before they expanded into a campaign against the country's broader coronavirus restrictions.

  • A man stands in front of a police officer as lorry drivers and supporters continue to protest against Covid-19 vaccine mandates, in Ottawa, Canada. Reuters
    A man stands in front of a police officer as lorry drivers and supporters continue to protest against Covid-19 vaccine mandates, in Ottawa, Canada. Reuters
  • A protester sings 'O Canada' as she is arrested after trying to push through a line of police officers. AP
    A protester sings 'O Canada' as she is arrested after trying to push through a line of police officers. AP
  • A protest lorry is towed. AFP
    A protest lorry is towed. AFP
  • Police hold a line as they work to bring a protest to an end. AP
    Police hold a line as they work to bring a protest to an end. AP
  • Police make an arrest. AP
    Police make an arrest. AP
  • A protester kneels in front of police officers. Reuters
    A protester kneels in front of police officers. Reuters
  • A demonstrator wears a tinfoil hat in front of a row of police. Reuters
    A demonstrator wears a tinfoil hat in front of a row of police. Reuters
  • A protester films on his phone during a police stand-off with demonstrators. AFP
    A protester films on his phone during a police stand-off with demonstrators. AFP
  • A protester is helped away after injuring his knee when a police line surged forward. AP
    A protester is helped away after injuring his knee when a police line surged forward. AP
  • Police clutch their batons as they move protesters back. AP
    Police clutch their batons as they move protesters back. AP
  • A demonstrator confronts police. AFP
    A demonstrator confronts police. AFP

Agencies contributed to this report.

Updated: February 25, 2022, 9:04 AM