A swarm of tiny nanorobots could be used to treat bleeds in the brain caused by aneurysms, opening “new frontiers in medicine”, scientists say.
Researchers have already trialled the technology on rabbits, which were injected with billions of magnetic nanobots made of blood-clotting drugs.
The nanobots, which are each around a twentieth of the size of a red blood cell, are made of three parts: a magnetic core known as an iron oxide nanoparticle, which is known to be safe for medical uses and which allows the nanorobots to be remotely guided to the right spot; a clotting drug agent called thrombin to block the aneurysm; and a protective coating that prevents the thrombin from being released in the wrong area.
Researchers guided the bots to the site of the aneurysm, a blood-filled bulge that can rupture and cause fatal bleeds, strokes or disabilities, and heated them to melt their coating, releasing the drug at the exact point it could prevent or stem bleeding.
Dr Qi Zhou of the University of Edinburgh’s School of Engineering, who co-led the study, told The National: "The nanorobots are essentially dissolved in the process and become part of the formed thrombus, which should gradually shrink in size due to blood supply cut-off, and be captured by immune cells for clean-up and natural healing."
He said nanorobots are set to open "new frontiers in medicine", potentially allowing us to carry out surgical repairs with fewer risks than conventional treatments and target drugs with pinpoint accuracy in hard-to-reach parts of the body.
The technology is likely to be in use in the coming decade.
"The next steps for us would be to test this technology in larger animals such as piglets or sheep for more comparable conditions to humans, with vessel networks and blood flow.
"We need to improve our control system for robust motion of the nanorobots to reach aneurysms located deeper in the brain. It is also important to make sure this treatment is safe and effective for the body in the long term through more preclinical studies. There is more work to be done, but we believe this technology has the potential to revolutionise the way we treat brain aneurysms."
The study showed nanobots have the potential to transport drugs to precise locations without the risk of leaking into the bloodstream, a key test of the technology’s safety and efficiency, researchers said.
The bots could also reduce the need for implants in the treatment of brain aneurysms, such as coils or mesh tubes, known as stents, and curb reliance on anti-blood-clotting drugs, which can cause bleeding and stomach problems.
Aneurysms cause about 500,000 deaths globally each year and are treated by surgery which can take hours due to the need to navigate a complex network of small blood vessels in the brain.
The study, published in the nanoscience and nanotechnology journal Small, was led by a team from the UK and China.
The same team has also developed nanorobots to remove blood clots, which they said also showed their potential in the treatment of strokes.
Killing of Qassem Suleimani
The specs
Engine: Direct injection 4-cylinder 1.4-litre
Power: 150hp
Torque: 250Nm
Price: From Dh139,000
On sale: Now
How to protect yourself when air quality drops
Install an air filter in your home.
Close your windows and turn on the AC.
Shower or bath after being outside.
Wear a face mask.
Stay indoors when conditions are particularly poor.
If driving, turn your engine off when stationary.
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Emergency
Director: Kangana Ranaut
Stars: Kangana Ranaut, Anupam Kher, Shreyas Talpade, Milind Soman, Mahima Chaudhry
Rating: 2/5
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If you go
Where to stay: Courtyard by Marriott Titusville Kennedy Space Centre has unparalleled views of the Indian River. Alligators can be spotted from hotel room balconies, as can several rocket launch sites. The hotel also boasts cool space-themed decor.
When to go: Florida is best experienced during the winter months, from November to May, before the humidity kicks in.
How to get there: Emirates currently flies from Dubai to Orlando five times a week.
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The specs
Engine: Dual 180kW and 300kW front and rear motors
Power: 480kW
Torque: 850Nm
Transmission: Single-speed automatic
Price: From Dh359,900 ($98,000)
On sale: Now
Arabian Gulf Cup FINAL
Al Nasr 2
(Negredo 1, Tozo 50)
Shabab Al Ahli 1
(Jaber 13)
Hydrogen: Market potential
Hydrogen has an estimated $11 trillion market potential, according to Bank of America Securities and is expected to generate $2.5tn in direct revenues and $11tn of indirect infrastructure by 2050 as its production increases six-fold.
"We believe we are reaching the point of harnessing the element that comprises 90 per cent of the universe, effectively and economically,” the bank said in a recent report.
Falling costs of renewable energy and electrolysers used in green hydrogen production is one of the main catalysts for the increasingly bullish sentiment over the element.
The cost of electrolysers used in green hydrogen production has halved over the last five years and will fall to 60 to 90 per cent by the end of the decade, acceding to Haim Israel, equity strategist at Merrill Lynch. A global focus on decarbonisation and sustainability is also a big driver in its development.
COMPANY PROFILE
Name: HyperSpace
Started: 2020
Founders: Alexander Heller, Rama Allen and Desi Gonzalez
Based: Dubai, UAE
Sector: Entertainment
Number of staff: 210
Investment raised: $75 million from investors including Galaxy Interactive, Riyadh Season, Sega Ventures and Apis Venture Partners
MATCH INFO
Uefa Champions League semi-final, first leg
Bayern Munich v Real Madrid
When: April 25, 10.45pm kick-off (UAE)
Where: Allianz Arena, Munich
Live: BeIN Sports HD
Second leg: May 1, Santiago Bernabeu, Madrid
Match info
Liverpool 3
Hoedt (10' og), Matip (21'), Salah (45 3')
Southampton 0
The fake news generation
288,000 – the number of posts reported as hate speech that were deleted by Facebook globally each month in May and June this year
11% – the number of Americans who said they trusted the news they read on Snapchat as of June 2017, according to Statista. Over a quarter stated that they ‘rarely trusted’ the news they read on social media in general
31% - the number of young people in the US aged between 10 and 18 who said they had shared a news story online in the last six months that they later found out was wrong or inaccurate
63% - percentage of Arab nationals who said they get their news from social media every single day.
FIXTURES
December 28
Stan Wawrinka v Pablo Carreno Busta, 5pm
Milos Raonic v Dominic Thiem, no earlier then 7pm
December 29 - semi-finals
Rafael Nadal v Stan Wawrinka / Pablo Carreno Busta, 5pm
Novak Djokovic v Milos Raonic / Dominic Thiem, no earlier then 7pm
December 30
3rd/4th place play-off, 5pm
Final, 7pm
RESULT
Valencia 3
Kevin Gameiro 21', 51'
Ferran Torres 67'
Atlanta 4
Josip Llicic 3' (P), 43' (P), 71', 82'
The five pillars of Islam
1. Fasting
2. Prayer
3. Hajj
4. Shahada
5. Zakat
MATCH INFO
Fixture: Ukraine v Portugal, Monday, 10.45pm (UAE)
TV: BeIN Sports
MATCH INFO
Barcelona 4 (Suarez 27', Vidal 32', Dembele 35', Messi 78')
Sevilla 0
Red cards: Ronald Araujo, Ousmane Dembele (Barcelona)
Dubai Bling season three
Cast: Loujain Adada, Zeina Khoury, Farhana Bodi, Ebraheem Al Samadi, Mona Kattan, and couples Safa & Fahad Siddiqui and DJ Bliss & Danya Mohammed
Rating: 1/5
The Sand Castle
Director: Matty Brown
Stars: Nadine Labaki, Ziad Bakri, Zain Al Rafeea, Riman Al Rafeea
Rating: 2.5/5
