Genetically modified mosquitoes have been released in a bid to reduce the risk of deadly infections in humans. EPA
Genetically modified mosquitoes have been released in a bid to reduce the risk of deadly infections in humans. EPA
Genetically modified mosquitoes have been released in a bid to reduce the risk of deadly infections in humans. EPA
Genetically modified mosquitoes have been released in a bid to reduce the risk of deadly infections in humans. EPA

Bacteria breakthrough makes it faster and cheaper to develop 'safe' mosquitoes


Gillian Duncan
  • English
  • Arabic

Scientists hope to rapidly increase the population of mosquitoes that cannot spread diseases after a breakthrough that could benefit mass breeding programmes.

Researchers at the University of Exeter have discovered a way to speed up mosquitoes' development, making it cheaper and quicker to farm them for release into the wild.

In control programmes, scientists genetically modify mosquitoes so they are either sterile or infected with a bacteria known as Wolbachia on the basis that the bacteria outcompetes viruses in their bodies, reducing the risk of deadly infections in humans. They are then released into the wild to mate with the biting females, which produce eggs that do not hatch, driving down the population of disease-carrying mosquitoes.

The new technique aids this process by speeding up the development of farmed mosquitoes. Working with the knowledge that some mosquitoes need bacteria to develop, scientists at the University of Exeter theorised that a particular species of bacteria – Asaia – could change the speed of the mosquitoes' growth.

When added to the water where the larvae develop, the bacteria led to an increase in their growth of 10 per cent, reducing the larval period from 10 days to nine, which could make it faster and cheaper to farm them.

“Very large-scale rearing has a number of logistical challenges,” Ben Raymond, professor of ecology and evolution at the University of Exeter, told The National. “Our experiments show that it’s possible to accelerate their development by around 10 per cent and so provide a significant cost saving for medical organisations involved in mass rearing.”

Prof Raymond said it is easy to culture the bacteria and only a small amount is needed to produce the effect. The scientists think the results would be reproduced in other places since they duplicated results in a second laboratory with different strains of mosquito. “So we think these results are robust,” he said. But there are some unknowns.

“Nevertheless, I would encourage anyone to check effects in local conditions,” he said. One specific unknown is whether or not the new bacteria will interact with the Wolbachia involved in reducing disease transmission, he added.

“The bacteria compete in malaria mosquitoes in the adults and it’s possible they may compete in [Aedes aegypti] mosquitoes also, although the context here is quite different as Asaia don’t persist beyond the larval stage and colonise adults in our experiments,” he said.

Thermal fogging is used against adult mosquitoes in the UAE. Jaime Puebla / The National
Thermal fogging is used against adult mosquitoes in the UAE. Jaime Puebla / The National

A recent study found that climate change is placing more people at risk of mosquito-borne diseases such as dengue fever, extending the seasonal window and creating frequent outbreaks that will become increasingly difficult to deal with.

The warning, shared in April, came after a report by The National revealed that global cases of dengue had risen sharply, with several Arab nations in particular experiencing an increase. Medics in Dubai said although the number of patients infected with the debilitating tropical disease requiring care was low, several cases had been reported to health authorities.

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What is dialysis?

Dialysis is a way of cleaning your blood when your kidneys fail and can no longer do the job.

It gets rid of your body's wastes, extra salt and water, and helps to control your blood pressure. The main cause of kidney failure is diabetes and hypertension.

There are two kinds of dialysis — haemodialysis and peritoneal.

In haemodialysis, blood is pumped out of your body to an artificial kidney machine that filter your blood and returns it to your body by tubes.

In peritoneal dialysis, the inside lining of your own belly acts as a natural filter. Wastes are taken out by means of a cleansing fluid which is washed in and out of your belly in cycles.

It isn’t an option for everyone but if eligible, can be done at home by the patient or caregiver. This, as opposed to home haemodialysis, is covered by insurance in the UAE.

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