Covid-19 vaccine efficacy against Delta variant declines after three months


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Covid-19 vaccines become less effective against the Delta variant three months after full vaccination, according to new research by the University of Oxford.

The results of the large UK study looked at how the Pfizer-BioNTech and AstraZeneca vaccines protect patients against Covid-19.

Probably you get some protection against more severe disease for a few years. The whole point of the vaccines is to stop people from getting ill and dying
Prof Paul Hunter,
University of East Anglia

Researchers found that 90 days after the second shot the vaccines' efficacy in preventing infections slipped to 75 per cent and 61 per cent respectively.

That was down from 85 per cent and 68 per cent respectively, seen two weeks after a second dose.

The decline in efficacy was more pronounced among those aged 35 years and over, than among younger case studies.

Scientists also found that when vaccinated people were infected with Delta, they had similar levels of virus in their bodies as those who had not had the injections.

This could imply that those who are vaccinated could still spread the virus. It also raises questions over whether herd immunity can be achieved even in countries of mostly vaccinated people.

Findings ‘not surprising’

Prof Paul Hunter, a professor in medicine and infectious diseases specialist at the University of East Anglia in the UK, said the results of the latest study were "not surprising".

He that while the vaccines' effectiveness at preventing mild infections starts to fall away in a matter of months, the shots continued to prevent severe disease for far longer.

Immunity against mild disease, from vaccination or previous infection, was, he said, "short-lived". But the immunity to the more severe viral pneumonia from Covid-19 that can result in hospital admission and death "lasts a lot longer".

"Probably you get some protection against more severe disease for a few years, so what this means is that the vaccines are not going to stop the spread of the virus. Most of us who work in the area have known this for at least six months," he said.

"Herd immunity is not and never was going to be achievable. The whole point of the vaccines is to stop people from getting ill and dying."

While the new study indicates a reduction in vaccine efficacy over time, Prof David Taylor, professor emeritus of pharmaceutical and public health policy at University College London, said the vaccines were performing "relatively well".

"The real [challenge] for the world is getting production up to the level so we can supply poor world [countries], which isn't happening at the moment," he said.

He said, however, that scientists and governments would look for enhanced vaccines that were more effective against the Delta variant and other variants, and that such "tweaked" shots could be used widely as boosters.

The UK survey, run by the University of Oxford and the Office for National Statistics, analysed more than three million PCR tests from a random sample of people.

The results are likely to encourage more countries to offer booster shots for fully vaccinated people. The policy is already in place in the UAE.

Health officials in the Emirates recommend that people have booster shots six months after their second vaccine dose, unless they are considered vulnerable, in which case they should have it after three months.

This week, US President Joe Biden announced that Americans who have had both doses of Pfizer-BioNTech or Moderna will be allowed a booster after eight months.

Israel this month started giving third doses of Pfizer-BioNTech to the elderly. Initial results show they have been 86 per cent effective for people aged 60 and over.

Ms Yang's top tips for parents new to the UAE
  1. Join parent networks
  2. Look beyond school fees
  3. Keep an open mind
Other workplace saving schemes
  • The UAE government announced a retirement savings plan for private and free zone sector employees in 2023.
  • Dubai’s savings retirement scheme for foreign employees working in the emirate’s government and public sector came into effect in 2022.
  • National Bonds unveiled a Golden Pension Scheme in 2022 to help private-sector foreign employees with their financial planning.
  • In April 2021, Hayah Insurance unveiled a workplace savings plan to help UAE employees save for their retirement.
  • Lunate, an Abu Dhabi-based investment manager, has launched a fund that will allow UAE private companies to offer employees investment returns on end-of-service benefits.
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Biosafety Level 1

The lowest safety level. These labs work with viruses that are minimal risk to humans.

Hand washing is required on entry and exit and potentially infectious material decontaminated with bleach before thrown away.

Must have a lock. Access limited. Lab does not need to be isolated from other buildings.

Used as teaching spaces.

Study microorganisms such as Staphylococcus which causes food poisoning.

Biosafety Level 2

These labs deal with pathogens that can be harmful to people and the environment such as Hepatitis, HIV and salmonella.

Working in Level 2 requires special training in handling pathogenic agents.

Extra safety and security precautions are taken in addition to those at Level 1

Biosafety Level 3

These labs contain material that can be lethal if inhaled. This includes SARS coronavirus, MERS, and yellow fever.

Significant extra precautions are taken with staff given specific immunisations when dealing with certain diseases.

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THREE POSSIBLE REPLACEMENTS

Khalfan Mubarak
The Al Jazira playmaker has for some time been tipped for stardom within UAE football, with Quique Sanchez Flores, his former manager at Al Ahli, once labelling him a “genius”. He was only 17. Now 23, Mubarak has developed into a crafty supplier of chances, evidenced by his seven assists in six league matches this season. Still to display his class at international level, though.

Rayan Yaslam
The Al Ain attacking midfielder has become a regular starter for his club in the past 15 months. Yaslam, 23, is a tidy and intelligent player, technically proficient with an eye for opening up defences. Developed while alongside Abdulrahman in the Al Ain first-team and has progressed well since manager Zoran Mamic’s arrival. However, made his UAE debut only last December.

Ismail Matar
The Al Wahda forward is revered by teammates and a key contributor to the squad. At 35, his best days are behind him, but Matar is incredibly experienced and an example to his colleagues. His ability to cope with tournament football is a concern, though, despite Matar beginning the season well. Not a like-for-like replacement, although the system could be adjusted to suit.

FIGHT CARD

Bantamweight Hamza Bougamza (MAR) v Jalal Al Daaja (JOR)

Catchweight 67kg Mohamed El Mesbahi (MAR) v Fouad Mesdari (ALG)

Lighweight Abdullah Mohammed Ali (UAE) v Abdelhak Amhidra (MAR)

Catchweight 73kg Mostafa Ibrahim Radi (PAL) v Yazid Chouchane (ALG)

Middleweight Yousri Belgaroui (TUN) v Badreddine Diani (MAR)

Catchweight 78kg Rashed Dawood (UAE) v Adnan Bushashy (ALG)

Middleweight Sallaheddine Dekhissi (MAR) v Abdel Emam (EGY)

Catchweight 65kg Rachid Hazoume (MAR) v Yanis Ghemmouri (ALG)

Lighweight Mohammed Yahya (UAE) v Azouz Anwar (EGY)

Catchweight 79kg Omar Hussein (PAL) v Souhil Tahiri (ALG)

Middleweight Tarek Suleiman (SYR) v Laid Zerhouni (ALG)

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MATCH INFO

Uefa Champions League semi-final, first leg

Barcelona v Liverpool, Wednesday, 11pm (UAE).

Second leg

Liverpool v Barcelona, Tuesday, May 7, 11pm

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Updated: August 21, 2021, 6:53 PM`